C4 Pre Workout Ingredients: 9 Facts From the Current Label

C4 PRE WORKOUT INGREDIENTS: 9 FACTS FROM THE CURRENT LABEL
C4 pre workout is one scoop of 8.9 g with 200 mg of caffeine, 2 g of beta alanine and 1 g of creatine nitrate. The current 5th Gen label also adds 100 mg of lentil peptides called PeptiPump.
This review reads the C4 pre workout ingredients line by line. For each one, we compare the label dose with the dose used in research. Label figures come from Cellucor; study figures come from PubMed, all listed at the end. For a stimulant free option, see our non stim pre workout guide.
C4 pre workout in three numbers
Three numbers on the C4 Original pre workout label tell you most of what the scoop will do.
Per scoop, printed on the panel
About as much as two small cups of coffee, as a rule of thumb (Cellucor label).
CarnoSyn, the cause of the tingle
Studies that raised muscle carnosine used 3.2 g a day or more (PMID 16554972).
Not the same as 1 g of creatine
Roughly two thirds of it is creatine by weight, by our arithmetic (Cellucor label).
Label figures come from the C4 Original 5th Gen Supplement Facts panel on cellucor.com, checked on 27 October 2026. The tub got a new look in 2026, but the 5th Gen formula and 30 servings per 267 g tub stay the same. We do not sell this product and take no payment for reviews.
What this C4 pre workout review covers
Every C4 pre workout ingredient on the current panel, with its dose.
Caffeine: how much is in C4 pre workout and how it compares with safety limits.
Doses vs studies for beta alanine, citrulline, arginine and creatine nitrate.
Not covered
Flavor rankings and prices. Both change; this is a label and evidence review.
C4 pre workout ingredients: the full label
Here are the C4 pre workout ingredients per scoop, in the order Cellucor prints them (Cellucor label).
| Ingredient | Per scoop | Group on the label |
|---|---|---|
| Caffeine anhydrous | 200 mg | Energy and focus |
| Huperzia serrata extract (1% huperzine A) | 5 mg | Energy and focus |
| CarnoSyn beta alanine | 2 g | Endurance |
| L-citrulline | 1.2 g | Velox blend (pump) |
| L-arginine | 1.2 g | Velox blend (pump) |
| PeptiPump lentil peptides | 100 mg | Velox blend (pump) |
| Creatine nitrate (NO3-T) | 1 g | Performance |
| Choline | 225 mg | Nutrient |
| Vitamin B6, folate, B12 | 3.4 mg, 100 mcg DFE, 6 mcg | Vitamins |
| Calories, carbs, sugar | 10 kcal, 1 g, 0 g | Nutrition |
Other ingredients are acids, flavors, flow agents, sucralose, acesulfame potassium and spirulina extract for color (Cellucor label).
Good news: every dose is printed. The Velox blend shows each part in grams, so nothing is hidden in a proprietary total.
The label warns that the product is for adults 18 and over, and not for pregnant or nursing women (Cellucor label).
How much caffeine is in C4 pre workout?
One scoop of C4 Original pre workout has 200 mg of caffeine anhydrous (Cellucor label). C4 Sport also has 200 mg, and C4 Ultimate has 300 mg (Cellucor product pages).
Caffeine is the ingredient with the best evidence. The caffeine position stand found benefits at 3 to 6 mg per kg of body weight (PMID 33388079).
The same paper says the minimum effective dose may be as low as 2 mg per kg. Very high doses, like 9 mg per kg, caused more side effects (PMID 33388079).
| Body weight | mg per kg from 1 scoop | Inside 3 to 6 mg/kg? |
|---|---|---|
| 60 kg | 3.3 | Yes |
| 70 kg | 2.9 | Just below |
| 80 kg | 2.5 | Below, above 2 |
| 100 kg | 2.0 | At the possible minimum |
One scoop is half of that daily amount. Coffee, energy drinks and a second scoop all count toward the same total (FDA).
The position stand notes that caffeine can affect sleep and anxiety, and that people respond differently (PMID 33388079).

Beta alanine in C4 pre workout: the tingle and the dose
Beta alanine raises carnosine in muscle, which buffers acid during hard efforts. The tingle on your skin is the known side effect.
The beta alanine position stand says 4 to 6 g a day for at least 2 to 4 weeks improved performance. Effects were clearest in efforts lasting 1 to 4 minutes (PMID 26175657).
It also says tingling can be reduced with divided doses of about 1.6 g, or a sustained release form (PMID 26175657).
In an early study, 3.2 g a day for 4 weeks raised muscle carnosine by about 42 percent (PMID 16554972).
A meta analysis found the clearest benefit in exercise lasting 60 to 240 seconds, and no clear benefit under 60 seconds (PMID 22270875).
Citrulline, arginine, PeptiPump and creatine nitrate
L-citrulline and L-arginine
C4 Original pre workout gives 1.2 g of L-citrulline and 1.2 g of L-arginine (Cellucor label).
The citrulline research used much larger doses of a different form. A meta analysis of 6 to 8 g of citrulline malate found about 6 percent more reps (PMID 34010809).
In one trial, 8 g of citrulline malate increased bench press reps and cut soreness (PMID 20386132). That form and dose are not what C4 contains.
A review of nitric oxide supplements found mixed results for arginine and citrulline in trained people (PMID 22260513).
PeptiPump
PeptiPump is listed as 100 mg of lentil peptides (Cellucor label). We found no human trial on PubMed for this ingredient. Treat any pump claim as unproven.
Creatine nitrate
Creatine nitrate is creatine bound to nitrate. Roughly two thirds of its weight is creatine, so 1 g gives about 0.67 g of creatine, by our arithmetic.
The creatine position stand describes a habitual intake of about 3 g a day (PMID 28615996). Higher loading doses are also used.
In a 28 day trial, 3 g of creatine nitrate a day was well tolerated and performed like 3 g of creatine monohydrate (PMID 27034623).
Huperzine A
Huperzia serrata extract at 5 mg with 1 percent huperzine A works out to about 50 mcg of huperzine A, by our arithmetic.
A 2023 review of memory supplements found mixed results for huperzine A (PMID 37603263). We found no strong trial for training focus.
C4 pre workout doses vs research doses
This chart shows how much of each research dose one scoop of C4 pre workout supplies.
| Ingredient | C4 per scoop | Research dose | Verdict |
|---|---|---|---|
| Caffeine | 200 mg | 3 to 6 mg/kg (PMID 33388079) | In range for many adults |
| Beta alanine | 2 g | 4 to 6 g a day for weeks (PMID 26175657) | Half dose |
| Creatine (from nitrate) | About 0.67 g | About 3 g a day (PMID 28615996) | Low |
| Citrulline | 1.2 g L-citrulline | 6 to 8 g citrulline malate (PMID 34010809) | Low, different form |
| PeptiPump | 100 mg | No human trial found | Unproven |

9 facts from the current C4 pre workout label
1. One scoop is 8.9 g, 30 scoops per tub. (Cellucor label)
2. 200 mg caffeine per scoop, printed on the panel (Cellucor label).
3. 2 g CarnoSyn beta alanine, half the 4 g daily research dose (PMID 26175657).
4. 1 g creatine nitrate, about 0.67 g of creatine by our arithmetic.
5. 1.2 g L-citrulline and 1.2 g L-arginine in the Velox blend (Cellucor label).
6. 100 mg PeptiPump lentil peptides, new on the 5th Gen panel (Cellucor label).
7. 5 mg Huperzia serrata extract, about 50 mcg huperzine A by our arithmetic.
8. 10 calories and 0 g sugar, sweetened with sucralose and acesulfame potassium (Cellucor label).
9. Adults 18 and over only, not for pregnant or nursing women (Cellucor label).
C4 pre workout: frequently asked questions
How much caffeine is in C4 pre workout?
C4 Original has 200 mg of caffeine per scoop. C4 Sport also has 200 mg, and C4 Ultimate has 300 mg (Cellucor product pages).
What are the main C4 pre workout ingredients?
Per scoop: 200 mg caffeine, 2 g beta alanine and 1 g creatine nitrate. The pump blend has 1.2 g L-citrulline, 1.2 g L-arginine and 100 mg PeptiPump, plus 5 mg Huperzia serrata extract (Cellucor label).
Is C4 pre workout bad for you?
For most healthy adults, one scoop gives 200 mg caffeine, half of the 400 mg a day FDA has cited for most adults (FDA). The label says adults 18 and over, not for pregnant or nursing women.
Why does C4 make my skin tingle?
The tingle comes from beta alanine. The position stand says divided doses of about 1.6 g or sustained release forms can reduce it (PMID 26175657).
Does C4 pre workout have creatine?
Yes, 1 g of creatine nitrate per scoop. That is about 0.67 g of creatine, below the habitual 3 g a day in the creatine position stand (PMID 28615996).
Is 200 mg of caffeine enough for performance?
Benefits were shown at 3 to 6 mg per kg, possibly from 2 mg per kg (PMID 33388079). 200 mg is 2.5 mg per kg for an 80 kg adult.
What is PeptiPump in C4?
PeptiPump is listed as 100 mg of lentil peptides in the Velox blend (Cellucor label). We found no human trial for it on PubMed.
Does citrulline in C4 increase reps?
Studies that found more reps used 6 to 8 g of citrulline malate (PMID 34010809). C4 has 1.2 g of L-citrulline.
Sources and further reading
Every figure on this page comes from one of the 13 sources below. That is two Cellucor pages, one FDA page and 10 papers checked against PubMed on 27 October 2026. Per kg doses, percent of research dose and the creatine and huperzine A amounts are our own arithmetic. Reference links are dofollow to support open science.
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Final Educational Note
This review is educational and is not medical advice. Label figures come from Cellucor pages on the date shown and may change; always read the tub you buy. People with heart conditions, high blood pressure, anxiety or caffeine sensitivity should talk to a doctor before using any stimulant pre workout.
MuscleScience does not sell supplements and is not paid for reviews. More guides sit on the supplements hub. Read more on the about page and in the full disclaimer.
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